Richard Watson Selected Research

RNS60

3/2018	RNS60 exerts therapeutic effects in the SOD1 ALS mouse model through protective glia and peripheral nerve rescue.
1/2018	Increase in Mitochondrial Biogenesis in Neuronal Cells by RNS60, a Physically-Modified Saline, via Phosphatidylinositol 3-Kinase-Mediated Upregulation of PGC1α.
1/2014	Enhancement of morphological plasticity in hippocampal neurons by a physically modified saline via phosphatidylinositol-3 kinase.
8/2012	Suppression of nuclear factor-κB activation and inflammation in microglia by physically modified saline.
1/2012	Protection of Tregs, suppression of Th1 and Th17 cells, and amelioration of experimental allergic encephalomyelitis by a physically-modified saline.

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Richard Watson Research Topics

Disease

6	Asthma (Bronchial Asthma) 01/2019 - 04/2004
4	Neoplasms (Cancer) 11/2007 - 11/2002
2	Pain (Aches) 10/2022 - 02/2006
2	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2018 - 08/2012
2	Inflammation (Inflammations) 01/2016 - 08/2012
2	Pancreatic Neoplasms (Pancreatic Cancer) 11/2007 - 04/2005
2	Respiratory Hypersensitivity 02/2007 - 07/2004
2	Prostatic Neoplasms (Prostate Cancer) 03/2006 - 02/2006
1	Hypertrophy 10/2022
1	Edema (Dropsy) 10/2022
1	Patellar Dislocation 01/2022
1	Eosinophilia 01/2019
1	Cough 01/2019
1	Demyelinating Diseases (Demyelinating Disease) 03/2018
1	Disease Progression 03/2018
1	Burns 07/2014
1	Opiate Overdose 01/2014
1	Dementia (Dementias) 01/2014
1	Amyloid Plaque 01/2014
1	Alzheimer Disease (Alzheimer's Disease) 01/2014
1	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 01/2012
1	Premature Ejaculation 05/2008
1	Infections 12/2005
1	Margins of Excision 04/2005
1	Neoplasm Metastasis (Metastasis) 04/2005
1	Uterine Cervical Neoplasms (Cancer of the Cervix) 11/2002
1	Prostatic Hyperplasia (Benign Prostatic Hyperplasia) 11/2002

Drug/Important Bio-Agent (IBA)

6	AllergensIBA 01/2019 - 04/2004
5	RNS60IBA 03/2018 - 01/2012
2	Proteins (Proteins, Gene)FDA Link 01/2014 - 01/2014
2	pranlukastIBA 07/2004 - 04/2004
1	AS 35IBA 01/2022
1	Capsaicin (Zostrix)FDA Link 01/2019
1	AntioxidantsIBA 03/2018
1	Interleukin-33IBA 01/2016
1	Therapeutic UsesIBA 07/2014
1	Naloxone (Narcan)FDA LinkGeneric 01/2014
1	CalciumIBA 01/2014
1	Amyloid (Amyloid Fibrils)IBA 01/2014
1	alpha- Amino- 3- hydroxy- 5- methyl- 4- isoxazolepropionic Acid (AMPA)IBA 01/2014
1	tau Proteins (tau Protein)IBA 01/2014
1	N-Methylaspartate (NMDA)IBA 01/2014
1	Transcription Factors (Transcription Factor)IBA 08/2012
1	Glycogen Synthase KinasesIBA 11/2007
1	Protein Kinases (Protein Kinase)IBA 11/2007
1	enzastaurinIBA 11/2007
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 02/2007
1	Budesonide (Pulmicort)FDA LinkGeneric 02/2007
1	Formoterol Fumarate (Oxis)FDA Link 02/2007
1	Fentanyl (Sublimaze)FDA LinkGeneric 02/2006
1	Bupivacaine (Bupivacaine Hydrochloride)FDA LinkGeneric 02/2006
1	Carrier Proteins (Binding Protein)IBA 12/2005
1	Indicators and Reagents (Reagents)IBA 04/2005
1	NF-kappa B (NF-kB)IBA 04/2005
1	S100 Calcium Binding Protein A6IBA 04/2005
1	Macrophage Inflammatory Proteins (Macrophage Inflammatory Protein 1)IBA 07/2004
1	LeukotrienesIBA 07/2004
1	Methacholine Chloride (Methacholine)FDA Link 07/2004
1	cysteinyl-leukotrieneIBA 07/2004
1	leukotriene D4 receptor (cysteinyl leukotriene receptor)IBA 07/2004
1	retinoic acid receptor betaIBA 11/2002
1	SteroidsIBA 11/2002
1	Phenobarbital (Luminal)FDA Link 11/2002

Therapy/Procedure

2	Therapeutics 05/2008 - 02/2007
2	Aftercare (After-Treatment) 11/2007 - 03/2006
2	Brachytherapy 03/2006 - 02/2006
1	Resistance Training 10/2022
1	Contact Lenses 07/2014
1	Immunomodulation 01/2012
1	Prostatectomy (Retropubic Prostatectomy) 03/2006
1	Radiotherapy 03/2006
1	Patient-Controlled Analgesia (Analgesia, Patient Controlled) 02/2006
1	Catheters 02/2006
1	Epidural Analgesia 02/2006
1	Pain Management 02/2006